The Dangers of Drug Use: A Comprehensive UK Guide
Introduction
Drug misuse remains a significant public health concern in the United Kingdom, with profound impacts on individuals, families, and communities. According to the Office for National Statistics, there were 4,859 deaths related to drug poisoning in England and Wales in 2021, representing the highest number since records began in 1993. This comprehensive guide examines the specific dangers associated with commonly misused substances in the UK context, providing evidence-based information about their effects, risks, and the support available for those affected.
Understanding the specific risks associated with different substances is crucial for harm reduction, informed decision-making, and effective treatment approaches. This guide aims to provide factual, non-judgmental information while acknowledging the serious health, social, and legal consequences that can arise from drug use.
Cannabis
Overview
Cannabis (also known as weed, marijuana, hash, or skunk) is the most widely used illegal drug in the UK. According to the 2019/20 Crime Survey for England and Wales, 7.8% of adults aged 16-59 had used cannabis in the previous year.
Forms and Consumption
In the UK, cannabis is commonly found as:
- Herbal cannabis ("weed" or "grass")
- Resin ("hash")
- High-potency skunk (typically grown domestically)
- Cannabis oil
- Edibles (increasingly common)
Short-term Effects
- Relaxation and altered sensory perception
- Impaired coordination and reaction time
- Increased heart rate
- Anxiety and paranoia (particularly with high-potency varieties)
- Short-term memory impairment
- Increased appetite
Long-term Risks
Mental Health Concerns:
The relationship between cannabis and mental health is particularly concerning in the UK context, where high-potency cannabis ("skunk") dominates the market. Research from King's College London has found that regular users of high-potency cannabis are five times more likely to develop psychosis compared to non-users.
Respiratory Issues:
When smoked with tobacco (common practice in the UK), cannabis poses additional risks including:
- Chronic bronchitis
- Lung inflammation
- Increased susceptibility to respiratory infections
- Heightened risk of lung cancer due to tobacco content
Dependency:
Approximately 10% of regular cannabis users develop dependency. NHS Digital reported that cannabis was the primary substance in 25% of all adults entering drug treatment in England during 2019/20.
Cognitive Effects:
Long-term, heavy use, particularly when started in adolescence, has been associated with:
- Reduced IQ (up to 8 points when use begins in adolescence)
- Impaired memory and attention
- Reduced educational achievement and life satisfaction
Legal Status and Penalties
Cannabis is a Class B controlled substance under the Misuse of Drugs Act 1971. Penalties include:
- Possession: Up to 5 years in prison, an unlimited fine, or both
- Supply and production: Up to 14 years in prison, an unlimited fine, or both
UK-Specific Concerns
- The average THC content in UK cannabis has increased significantly over the past two decades, from approximately 4% to 14% in herbal cannabis
- Cannabis is often mixed with synthetic cannabinoids in the UK, creating unpredictable and potentially dangerous effects
- The UK has seen a rise in cannabis-related hospital admissions, with a 15% increase between 2013 and 2018
Support Resources
- FRANK: 0300 123 6600 or talktofrank.com
- NHS cannabis-specific support: nhs.uk/live-well/addiction-support/cannabis-get-help
Cocaine
Overview
Cocaine use has been increasing in the UK, with the European Monitoring Centre for Drugs and Drug Addiction reporting that the UK has the highest prevalence of cocaine use among young adults in Europe. The drug is a powerful stimulant derived from the coca plant native to South America.
Forms and Consumption
In the UK market, cocaine is typically found as:
- Cocaine hydrochloride powder (often referred to as "coke" or "charlie")
- Crack cocaine ("rocks" or "stones")
Short-term Effects
- Intense euphoria and energy
- Increased alertness and confidence
- Suppressed appetite
- Elevated heart rate and blood pressure
- Hyperthermia (increased body temperature)
- Constricted blood vessels
- Dilated pupils
- Anxiety, paranoia, and agitation
Long-term Risks
Cardiovascular Damage:
Cocaine significantly increases the risk of serious cardiovascular problems, including:
- Heart attacks (users have a 24-fold increased risk during the first hour after use)
- Stroke
- Aortic dissection
- Myocarditis (inflammation of the heart muscle)
- Cardiomyopathy (deterioration of heart muscle)
Mental Health Issues:
- Severe anxiety and panic disorders
- Paranoid psychosis
- Depression
- Increased risk of suicidal thoughts
Physical Health Deterioration:
- Nasal damage (septum perforation, chronic rhinitis)
- Respiratory problems (when smoked as crack)
- Severe weight loss and malnutrition
- Increased risk of infections due to compromised immune system
Dependency:
Cocaine is highly addictive, with approximately 21% of users developing dependency. The UK has seen a 32% increase in people seeking treatment for cocaine addiction between 2015 and 2020.
Specific Risks of Crack Cocaine
Crack cocaine, which is smoked rather than snorted, presents additional risks:
- More intense but shorter-lasting effects
- Higher addiction potential
- Greater risk of respiratory damage
- Increased association with chaotic use patterns
- Higher rates of associated crime and social problems
Adulterants in UK Cocaine
UK cocaine purity varies significantly (typically 20-60%), with common adulterants including:
- Levamisole (a veterinary deworming agent that can cause agranulocytosis)
- Benzocaine (local anaesthetic)
- Phenacetin (banned painkiller linked to kidney damage)
- Caffeine
- Laundry detergents and other household chemicals
Legal Status and Penalties
Cocaine is a Class A controlled substance under the Misuse of Drugs Act 1971:
- Possession: Up to 7 years in prison, an unlimited fine, or both
- Supply and production: Up to life in prison, an unlimited fine, or both
UK-Specific Concerns
- Cocaine-related deaths in England and Wales have increased for eight consecutive years, reaching 777 deaths in 2020
- The average purity of cocaine in the UK has increased significantly in recent years
- The UK has the highest rate of cocaine use among young adults in Europe
Support Resources
- FRANK: 0300 123 6600
- Cocaine Anonymous UK: 0800 612 0225 or cocaineanonymous.org.uk
- NHS Addiction Services: nhs.uk/service-search/other-services/Substance-misuse/LocationSearch/340
MDMA (Ecstasy)
Overview
MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy, is a synthetic drug with stimulant and hallucinogenic properties. It remains popular in the UK club and festival scene, with the highest rate of use among young adults in Europe.
Forms and Consumption
In the UK, MDMA is typically found as:
- Pills/tablets (ecstasy) in various colours, shapes, and designs
- Crystals or powder (often referred to as "mandy" or "molly")
Short-term Effects
- Intense feelings of euphoria and emotional warmth
- Enhanced sensory experiences
- Increased energy and alertness
- Distorted sense of time
- Increased heart rate and blood pressure
- Elevated body temperature
- Dehydration
- Jaw clenching and teeth grinding
- Dilated pupils
Long-term Risks
Neurotoxicity:
Research suggests MDMA can damage serotonin-producing neurons in the brain, potentially leading to:
- Memory problems
- Attention difficulties
- Impaired executive function
- Increased impulsivity
- Depression and anxiety
Hyperthermia and Related Complications:
MDMA interferes with the body's temperature regulation, which can lead to:
- Dangerous overheating (particularly in club environments)
- Dehydration
- Electrolyte imbalances
- Rhabdomyolysis (breakdown of muscle tissue)
- Kidney failure
- Liver damage
- Death in severe cases
Cardiovascular Risks:
- Irregular heartbeat (arrhythmias)
- Heart attack
- Stroke
- Sudden cardiac death (rare but documented)
Psychological Effects:
- "Mid-week blues" or "Tuesday blues" (temporary depression following weekend use)
- Anxiety disorders
- Sleep disturbances
- Potential exacerbation of underlying mental health conditions
Specific UK Concerns
High-Strength Pills:
The UK has seen a significant increase in high-dose MDMA tablets, with some containing 250-300mg of MDMA (2-3 times a typical dose). The European Monitoring Centre for Drugs and Drug Addiction has issued specific warnings about high-strength pills in the UK market.
Adulteration:
UK testing services have found MDMA products containing:
- PMA/PMMA (particularly dangerous substances with delayed onset)
- N-ethylpentylone and other cathinones
- Methamphetamine
- Caffeine
- Various novel psychoactive substances
MDMA-Related Deaths:
The UK has experienced a concerning increase in MDMA-related deaths, with 92 deaths in England and Wales in 2018, up from 56 in 2017. Many of these deaths are associated with high-strength pills and environmental factors (overheating in clubs).
Harm Reduction in the UK Context
- The Loop and other drug checking services operate at some UK festivals
- "Start low, go slow" approach recommended, especially with unknown pills
- Staying hydrated but not overhydrating (approximately 500ml per hour)
- Taking regular breaks from dancing
- Avoiding mixing with alcohol or other drugs
Legal Status and Penalties
MDMA is a Class A controlled substance under the Misuse of Drugs Act 1971:
- Possession: Up to 7 years in prison, an unlimited fine, or both
- Supply and production: Up to life in prison, an unlimited fine, or both
Support Resources
- FRANK: 0300 123 6600
- The Loop (drug safety testing and harm reduction): wearetheloop.org
- Crew 2000 (Scotland): 0131 220 3404 or crew.scot
Heroin
Overview
Heroin (diamorphine) is a highly addictive opioid drug derived from morphine. While overall prevalence has declined in recent years, heroin remains responsible for the majority of drug-related deaths in the UK, with significant public health implications.
Forms and Consumption
In the UK market, heroin typically appears as:
- Brown powder (most common in the UK)
- White powder (less common)
- Black tar heroin (rare in the UK)
Common methods of use in the UK include:
- Smoking ("chasing the dragon")
- Injecting
- Snorting (less common)
Short-term Effects
- Intense euphoria ("rush")
- Pain relief
- Sedation and drowsiness
- Nausea and vomiting
- Constricted pupils
- Dry mouth
- Clouded thinking
- Alternating between consciousness and semi-consciousness ("nodding")
- Respiratory depression
Long-term Risks
Dependency:
Heroin is extremely addictive, with physical dependency developing rapidly. The UK has approximately 250,000-300,000 opioid-dependent individuals, with heroin being the primary drug of concern.
Overdose:
Heroin significantly depresses respiratory function, which can lead to:
- Respiratory arrest
- Hypoxic brain injury
- Death
In 2020, there were 1,337 heroin-related deaths in England and Wales, representing approximately 50% of all drug misuse deaths.
Injection-Related Risks:
- Blood-borne virus transmission (HIV, hepatitis B and C)
- Bacterial infections
- Endocarditis (heart valve infection)
- Abscesses and cellulitis
- Venous damage and collapse
- Deep vein thrombosis
Physical Health Deterioration:
- Severe constipation
- Dental problems
- Malnutrition
- Reduced immune function
- Chronic respiratory issues
- Sexual dysfunction and reproductive issues
Social and Psychological Impact:
- Breakdown of relationships
- Unemployment
- Homelessness
- Criminal activity to fund addiction
- Depression and anxiety
- Post-traumatic stress disorder (often pre-existing but exacerbated)
UK-Specific Concerns
Adulteration:
UK heroin is typically 20-40% pure, with common adulterants including:
- Caffeine
- Paracetamol
- Benzodiazepines
- Fentanyl and its analogues (increasingly concerning)
Fentanyl Contamination:
While not as prevalent as in North America, the UK has seen increasing cases of fentanyl-adulterated heroin, which significantly increases overdose risk due to fentanyl's potency (50-100 times stronger than heroin).
Aging Population of Users:
The UK has an aging cohort of heroin users, with associated health complications including:
- Chronic obstructive pulmonary disease
- Cardiovascular disease
- Liver cirrhosis
- Cancer
- Mental health disorders
Harm Reduction and Treatment in the UK
Opioid Substitution Therapy (OST):
- Methadone and buprenorphine prescribed through NHS drug services
- Approximately 140,000 people receiving OST in England
Naloxone Distribution:
- Take-home naloxone programmes to reverse overdoses
- Available through drug services, some pharmacies, and homeless services
Needle and Syringe Programmes:
- Widespread availability through pharmacies and specialist services
- Provides clean injecting equipment to reduce infection risks
Legal Status and Penalties
Heroin is a Class A controlled substance under the Misuse of Drugs Act 1971:
- Possession: Up to 7 years in prison, an unlimited fine, or both
- Supply and production: Up to life in prison, an unlimited fine, or both
Support Resources
- FRANK: 0300 123 6600
- NHS Addiction Services: nhs.uk/service-search/other-services/Substance-misuse/LocationSearch/340
- UK Narcotics Anonymous: 0300 999 1212 or ukna.org
Ketamine
Overview
Ketamine is a dissociative anaesthetic that has legitimate medical uses but has become increasingly popular as a recreational drug in the UK. The country has one of the highest rates of ketamine use in Europe, particularly among young adults and in the nightlife scene.
Forms and Consumption
In the UK, ketamine is typically found as:
- White crystalline powder
- Small crystals ("shards")
- Liquid (less common, typically diverted from medical supplies)
Common methods of use include:
- Snorting (most common)
- Oral consumption
- Intramuscular injection (less common)
Short-term Effects
- Dissociation from body and environment
- Altered perception of reality
- Hallucinations
- Feeling of detachment or floating
- Reduced sensitivity to pain
- Impaired motor function
- Slurred speech
- Confusion and disorientation
- Nausea and vomiting
- At high doses, the "K-hole" (profound dissociative state)
Long-term Risks
Urinary Tract Damage:
Ketamine-induced ulcerative cystitis is a significant concern, particularly prevalent in the UK where long-term ketamine use is more common. Symptoms include:
- Frequent and painful urination
- Blood in urine
- Incontinence
- Reduced bladder capacity
- In severe cases, surgical bladder removal may be necessary
Research from Bristol Urological Institute suggests that up to 30% of regular ketamine users experience urinary symptoms.
Cognitive Impairment:
- Memory problems
- Attention deficits
- Decreased cognitive processing speed
- Impaired verbal learning
Psychological Effects:
- Dependency (primarily psychological)
- Depression
- Anxiety and panic attacks
- Psychosis-like symptoms
- Perceptual disturbances that persist beyond intoxication
Physical Health Issues:
- Abdominal pain ("K-cramps")
- Liver damage
- Gallbladder inflammation
- Gastrointestinal issues
Specific UK Concerns
Increasing Prevalence:
The Crime Survey for England and Wales has shown a significant increase in ketamine use, particularly among 16-24 year olds, with usage rates doubling between 2012/13 and 2019/20.
Purity and Adulteration:
UK ketamine purity varies widely (typically 30-90%), with common adulterants including:
- Methoxetamine (MXE) and other novel dissociatives
- Caffeine
- Creatine
- Synthetic cathinones
Ketamine-Related Deaths:
While direct ketamine overdose deaths are relatively rare, the UK has seen an increase in ketamine-related fatalities, often involving accidents or polydrug use. The Office for National Statistics reported 23 ketamine-related deaths in England and Wales in 2019, up from 18 in 2018.
Harm Reduction in the UK Context
- Start with very small amounts, particularly with unfamiliar batches
- Avoid mixing with alcohol, opioids, or other depressants
- Use in safe environments with trusted friends
- Remain seated or lying down when using
- Be aware of the risk of accidents due to impaired coordination and pain perception
Legal Status and Penalties
Ketamine is a Class B controlled substance under the Misuse of Drugs Act 1971:
- Possession: Up to 5 years in prison, an unlimited fine, or both
- Supply and production: Up to 14 years in prison, an unlimited fine, or both
Support Resources
- FRANK: 0300 123 6600
- Ketamine Addiction Support: ketamineaddictionsupport.org
- The Bristol Urological Institute (for ketamine bladder syndrome): 0117 414 0513
Benzodiazepines
Overview
Benzodiazepines are a class of sedative medications commonly prescribed for anxiety, insomnia, and seizures. In the UK, both diverted prescription benzodiazepines and illicitly manufactured versions are widely misused, with significant health and social consequences.
Common Types in the UK
Prescribed Benzodiazepines:
- Diazepam (Valium)
- Lorazepam (Ativan)
- Temazepam
- Clonazepam (Rivotril)
- Alprazolam (Xanax) - less commonly prescribed in the UK but often obtained illicitly
Illicit Benzodiazepines:
- Counterfeit "street Valium" (often containing variable doses or other substances)
- Etizolam (technically a thienodiazepine)
- Flualprazolam
- Clonazolam
- Diclazepam
Short-term Effects
- Reduced anxiety
- Sedation and drowsiness
- Muscle relaxation
- Impaired coordination
- Slurred speech
- Confusion
- Memory impairment
- Reduced inhibition
- At high doses: extreme sedation, respiratory depression
Long-term Risks
Dependency and Withdrawal:
Benzodiazepines are highly addictive, with physical dependency developing within 3-4 weeks of regular use. Withdrawal can be severe and potentially life-threatening, with symptoms including:
- Rebound anxiety and insomnia
- Sensory hypersensitivity
- Tremors
- Muscle pain and stiffness
- Seizures
- Psychosis
- In severe cases, delirium tremens
Cognitive Impairment:
- Memory problems (particularly forming new memories)
- Reduced attention and concentration
- Impaired learning ability
- "Benzo brain fog" - general cognitive slowing
Mental Health Issues:
- Depression
- Paradoxical reactions (increased anxiety, irritability)
- Emotional blunting
- Increased risk of suicidal thoughts
- Agoraphobia
Physical Health Concerns:
- Increased risk of falls and fractures, particularly in older adults
- Respiratory depression (especially when combined with alcohol or opioids)
- Increased risk of pneumonia
- Potential links to dementia with long-term use
UK-Specific Concerns
"Street Benzos" Crisis:
Scotland in particular has experienced a public health crisis related to illicit benzodiazepines, with "street Valium" implicated in a large proportion of drug-related deaths. In 2020, benzodiazepines were involved in 974 drug deaths in Scotland.
Counterfeit Medications:
The UK has seen a significant increase in counterfeit benzodiazepines, particularly fake Xanax tablets, which may contain:
- Variable doses of alprazolam (sometimes many times the therapeutic dose)
- Other benzodiazepines or novel substances
- Fentanyl or other opioids
- No active ingredient at all
Polydrug Use:
Benzodiazepines are frequently used alongside other substances in the UK, particularly:
- Alcohol (dramatically increasing overdose risk)
- Opioids (responsible for many overdose deaths)
- Stimulants (to manage "comedowns")
Prescription vs. Illicit Use
The UK faces dual challenges with benzodiazepines:
- Prescribed dependency: Patients becoming dependent on legally prescribed benzodiazepines
- Illicit market: A growing street market for both diverted medications and illicitly manufactured benzodiazepines
Legal Status and Penalties
Most benzodiazepines are Class C controlled substances under the Misuse of Drugs Act 1971:
- Possession without a prescription: Up to 2 years in prison, an unlimited fine, or both
- Supply and production: Up to 14 years in prison, an unlimited fine, or both
Some novel benzodiazepines are controlled under the Psychoactive Substances Act 2016.
Support Resources
- FRANK: 0300 123 6600
- Battle Against Tranquillisers (BAT): 0844 826 9317
- Prescribed Medication Support Service: prescribeddrug.info
- NHS Benzodiazepine withdrawal support: nhs.uk/live-well/addiction-support/addiction-to-prescription-drugs/
Synthetic Cannabinoids (Spice/K2)
Overview
Synthetic cannabinoids, commonly known as "Spice" or "K2" in the UK, are human-made chemicals designed to mimic the effects of THC, the main psychoactive component in cannabis. Despite often being marketed as "legal highs" in the past, these substances are now illegal and have been associated with severe health risks.
Forms and Consumption
In the UK, synthetic cannabinoids are typically found as:
- Dried plant material sprayed with chemicals
- Liquid form for vaping
- Crystalline powder (less common)
Common methods of use include:
- Smoking (mixed with tobacco or in a pipe)
- Vaping
- Less commonly, oral consumption
Short-term Effects
- Altered perception
- Extreme anxiety and paranoia
- Confusion and disorientation
- Agitation and aggression
- Rapid heart rate
- High blood pressure
- Nausea and vomiting
- Seizures
- Hallucinations
- Psychosis
- Loss of consciousness
Long-term Risks
Mental Health Issues:
- Persistent psychosis
- Severe anxiety disorders
- Depression
- Suicidal ideation
- Cognitive impairment
Physical Health Concerns:
- Kidney damage
- Liver toxicity
- Cardiovascular problems
- Respiratory issues
- Stroke
- Seizure disorders
Dependency:
Synthetic cannabinoids can cause severe dependency, with withdrawal symptoms including:
- Intense cravings
- Insomnia
- Irritability and aggression
- Nausea and vomiting
- Sweating
- Tremors
UK-Specific Concerns
Prison and Homeless Populations:
Synthetic cannabinoids have become particularly problematic in UK prisons and among homeless populations due to their low cost and difficulty in detection by standard drug tests. HM Inspectorate of Prisons has highlighted the destabilizing effect of these substances in the prison system.
Unpredictable Potency:
UK testing has found extreme variations in potency, with some samples containing synthetic cannabinoids hundreds of times more potent than natural THC. This makes dosing extremely unpredictable and increases overdose risk.
Ambulance Callouts and Hospital Admissions:
The UK has seen significant increases in emergency service callouts related to synthetic cannabinoids, with users often presenting with severe symptoms requiring intensive care. In Manchester alone, there were over 500 Spice-related emergency callouts in a three-month period in 2017.
Deaths:
The Office for National Statistics reported 60 deaths involving synthetic cannabinoids in England and Wales in 2018, up from 24 in 2015, demonstrating the increasing danger of these substances.
Legal Status and Penalties
Synthetic cannabinoids are controlled under the Psychoactive Substances Act 2016 and as Class B substances under the Misuse of Drugs Act 1971:
- Possession: Up to 5 years in prison, an unlimited fine, or both
- Supply and production: Up to 14 years in prison, an unlimited fine, or both
Support Resources
- FRANK: 0300 123 6600
- NHS Addiction Services: nhs.uk/service-search/other-services/Substance-misuse/LocationSearch/340
- Release (legal advice on drugs): 020 7324 2989 or release.org.uk
Prescription Opioids
Overview
Prescription opioid misuse has become an increasing concern in the UK, though not to the same extent as the crisis in North America. These medications, prescribed for pain management, carry significant risks when misused or taken non-medically.
Common Types in the UK
Prescribed Opioid Medications:
- Codeine (often in combination products with paracetamol)
- Dihydrocodeine (DF118, DHC)
- Tramadol
- Morphine (MST, Oramorph)
- Oxycodone (OxyContin, OxyNorm)
- Fentanyl patches
- Buprenorphine (Subutex, Temgesic)
Short-term Effects
- Pain relief
- Euphoria
- Sedation
- Nausea and vomiting
- Constipation
- Respiratory depression
- Constricted pupils
- Itching
- Drowsiness
Long-term Risks
Dependency and Addiction:
Physical dependency can develop within weeks of regular use, with tolerance requiring increasing doses to achieve the same effect. The UK has seen a 22% increase in opioid prescriptions between 2008 and 2018.
Overdose:
Prescription opioids can cause fatal respiratory depression, particularly when:
- Taken in higher than prescribed doses
- Combined with alcohol or benzodiazepines
- Used by individuals without opioid tolerance
Physical Health Issues:
- Severe constipation
- Hormonal imbalances
- Reduced immune function
- Sleep-disordered breathing
- Increased sensitivity to pain (hyperalgesia)
- Dental problems
Mental Health Concerns:
- Depression
- Anxiety
- Cognitive impairment
- Emotional blunting
UK-Specific Concerns
Increasing Prescribing Rates:
Public Health England reported that 5.6 million people in England (12.8% of the adult population) received a prescription for an opioid in 2018, a significant increase from previous years.
Over-the-Counter Codeine:
The UK allows pharmacy sales of low-dose codeine products (e.g., codeine/paracetamol combinations), which can lead to misuse and dependency. These products are subject to abuse despite restrictions on quantity and pharmacist oversight.
Diverted Medications:
There is a growing concern about prescription opioids being diverted to the illicit market, with online sales and "doctor shopping" being particular issues.
Deaths:
Prescription opioid-related deaths have increased in the UK, with tramadol in particular being implicated in a significant number of fatalities. Following its reclassification as a controlled drug in 2014, tramadol-related deaths decreased, but overall prescription opioid deaths continue to rise.
Harm Reduction and Treatment
UK Clinical Guidelines:
The UK has implemented stricter prescribing guidelines for opioids, emphasizing:
- Short-term use where possible
- Regular review of effectiveness
- Gradual tapering rather than abrupt discontinuation
- Non-pharmacological pain management alternatives
Treatment Options:
- Opioid substitution therapy (methadone, buprenorphine)
- Psychological support
- Pain management programmes
- Residential rehabilitation
Legal Status and Penalties
Most prescription opioids are Class A or Class B controlled substances under the Misuse of Drugs Act 1971:
- Possession without a prescription: Up to 5-7 years in prison, depending on classification
- Supply and production: Up to 14 years to life in prison, depending on classification
Support Resources
- FRANK: 0300 123 6600
- Pain Concern: 0300 123 0789 or painconcern.org.uk
- NHS Addiction Services: nhs.uk/service-search/other-services/Substance-misuse/LocationSearch/340
Alcohol
Overview
While legal and socially accepted, alcohol remains the most widely misused psychoactive substance in the UK, with significant health, social, and economic consequences. According to Public Health England, alcohol is the leading risk factor for deaths among people aged 15-49 in the UK.
Consumption in the UK
- 57% of adults in England reported drinking alcohol in the previous week (2019)
- 24% of adults in England regularly drink over the Chief Medical Officer's low-risk guidelines
- 4% of adults in England (approximately 1.6 million people) have some level of alcohol dependency
Short-term Effects
- Reduced inhibition
- Impaired coordination and reaction time
- Slurred speech
- Impaired judgment
- Mood changes
- Nausea and vomiting
- Dehydration
- Temporary memory loss ("blackouts")
- In high doses: respiratory depression, unconsciousness
Long-term Risks
Physical Health Damage:
- Liver disease (alcoholic hepatitis, cirrhosis)
- Cardiovascular problems (hypertension, cardiomyopathy)
- Digestive issues (pancreatitis, gastritis)
- Neurological damage (Wernicke-Korsakoff syndrome)
- Increased cancer risk (mouth, throat, esophagus, liver, breast)
- Weakened immune system
Mental Health Issues:
- Depression and anxiety
- Increased suicide risk
- Memory problems and cognitive decline
- Alcohol-related brain damage
- Psychosis (in severe cases)
Dependency and Withdrawal:
Alcohol dependency affects approximately 1.6 million people in the UK. Withdrawal can be severe and potentially life-threatening, with symptoms including:
- Tremors
- Anxiety
- Nausea and vomiting
- Insomnia
- Hallucinations
- Seizures
- Delirium tremens (in severe cases)
Social and Economic Impact:
- Relationship breakdown
- Domestic violence (alcohol is a factor in 39% of domestic violence cases)
- Workplace absenteeism and reduced productivity
- Financial problems
- Criminal justice involvement
UK-Specific Concerns
Binge Drinking Culture:
The UK has a pronounced binge drinking culture, with 27% of drinkers in Great Britain binge drinking on their heaviest day (defined as exceeding 8 units for men or 6 units for women).
Economic Cost:
The annual cost of alcohol harm to the UK economy is estimated at £21-52 billion, including costs to the NHS, crime and policing, workplace productivity, and social services.
NHS Burden:
There were 358,000 hospital admissions in 2018/19 where the primary reason was attributable to alcohol, representing a significant burden on the NHS.
Deaths:
In 2019, there were 7,565 alcohol-specific deaths

